Evaluation of the Antidiabetic Effect of Aqueous Crude Extract of Seed, Leaf and Stem of Linum usitatissimum on Streptozotocin-Induced Diabetic Rats

Diabetes is a metabolic disorder characterized by persistent high glucose level. Linum usitatissimum (flaxseed) which rich in fibre and essential fatty acid one of the functional foods used management diabetes mellitus. The aim this study to evaluate antidiabetic effect L. usititatissimum seed leaf stem on streptozotocin induced diabetic rats see part more potent diabetes. Thirty (30) albino weighing 170-200g were for was intraperitoneal injection 55mg/kg body weight streptozotocin. randomly divided into six (6) groups are as follows: Group A; normal control, B; control group, C; standard drug (Glibenclamide), D-F adminstered different parts crude plants extract. phytochemistry analysis showed that possessed bioactive component followed lastly stem. phytochemical present include: alkaloid, flavonoids, tannins, saponins, terpene, steroid, balsam, carbohydrate phenol. Across received aqueous extract significant reduction blood level, however, (6.60 ± 2.450bc) difference when compared (7.65 1.100bc) (7.95 2.650bc) respectively. On other hand, protein albumin biomarkers significantly (P ≤0.005) increased across groups. Crude also antihyperlidemic properties, improved serum enzymes electrolytes levels. There positive impact hematological parameters. In accordance with results investigation, Usititatissimum antihyperglycemic antihyperlipidemic agent streptozotocin-induced although, demonstrated biochemical haematological This result might be various plant.